Diabetes

The research focuses on the use of new technologies to improve outcomes for people with diabetes. We undertake randomised controlled trials to evaluate the efficacy and safety of automated insulin delivery systems for people with type 1 diabetes, type 2 diabetes and cystic fibrosis related diabetes in the outpatient setting.

 Studies currently open to recruitment

COYOTE

The COYOTE study aims to find out if using an automated insulin delivery system (also called a closed-loop system) can improve glucose levels in people with type 2 diabetes compared with standard insulin injections and a glucose sensor.

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REACTIVATE

The REACTIVATE study (Phase 2) aims to find out if using an automated insulin system (also called a closed-loop system) can help people with type 2 diabetes achieve remission of their diabetes compared with standard diabetes medications and a glucose sensor.

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Beta-PRESERVE

A study to investigate the efficacy and safety of teplizumab compared with placebo  in participants  aged 1 to 25 years of age with recently diagnosed stage 3 type 1 diabetes (T1D).

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Baricade-DELAY

This study is investigating whether baricitinib delays the onset of Stage 3 Type 1 diabetes in participants with Stage 1b or Stage 2 Type 1 diabetes.

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Baricade-PRESERVE

The Baricade-PRESERVE is a study to learn more about baricitinib, a possible new medicine for the treatment of newly diagnosed type 1 diabetes. 

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